Endocrine Abstracts

Objective: It is very important to determine the malignancy risk in thyroid nodules for to improve therapeutic strategies. In this study we attempted to evaluate the relationship of doppler (DUS) and B- mode ultrasonographic (BUS) features of thyroid nodules with fine needle aspiration (FNA) findings.Method: 111 patients which have been followed between March and September 2004 were evaluated with ultrasonography and ultrasound guided FNA was performed i...

Congenital morphological thyroid abnormalities can be classified as hemiagenesis or total agenesis, lingual thyroid, substernal thyroid, thyroglossal ductus remnant. Hemiagenesis with absence of one lobe or lobe and isthmus is very rare, it was found in 4 of 7000 scans in one study. The left lobe is absent four times as often as the right lobe, and women are about three times more likely than men to have this developmental defect. Usually diagnosing this condition is not very ...

Leptin, which is secreted mainly by adipocytes and some other tissues including pituitary, informs the brain about the mass of adipose tissue and has an important role in energy homeostasis. We have previously shown that melatonin decreases circulating leptin levels. Whether melatonin has an effect on leptin synthesis in pituitary is currently unknown. Therefore, the aim of this study was to immunohistochemically examine the effects of pinealectomy and administration of melato...

This study was undertaken to examine the effects of leptin on testicular histology in mice. Animals were divided into two groups. Group I served as controls. Mice in Group II were injected daily with leptin for five days. All animals were killed by decapitation at the end of the experiment. The testes were removed and weighed out. Some of the testicular tissue specimens were used for light and electron microscopic examination. The remaining samples were processed for semiquant...